Download e-book for iPad: Aggressive Breast Cancer by Regina H. DeFrina

By Regina H. DeFrina

ISBN-10: 1617618640

ISBN-13: 9781617618642

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Pinkas-Kramarski, R; Eilam, R; Spiegler, O; Lavi, S; Liu, N; Chang, D; Wen, D; Schwartz, M; Yarden, Y. Brain neurons and glial cells express neu 38 Myra F. Barginear and Daniel R. Budman differentiation factor/heregulin: A survival factor for astrocytes. Proc Natl Acad Sci U S A, 1994, 91, 9387-9391. Perez-Soler, R. Her1/egfr targeting: Refining the strategy. Oncologist, 2004, 9, 58-67. Di Fiore, PP; Pierce, JH; Kraus, MH; Segatto, O; King, CR; Aaronson, SA. Erbb2 is a potent oncogene when overexpressed in nih/3t3 cells.

Brain neurons and glial cells express neu 38 Myra F. Barginear and Daniel R. Budman differentiation factor/heregulin: A survival factor for astrocytes. Proc Natl Acad Sci U S A, 1994, 91, 9387-9391. Perez-Soler, R. Her1/egfr targeting: Refining the strategy. Oncologist, 2004, 9, 58-67. Di Fiore, PP; Pierce, JH; Kraus, MH; Segatto, O; King, CR; Aaronson, SA. Erbb2 is a potent oncogene when overexpressed in nih/3t3 cells. Science, 1987, 237, 178-182. Di Marco, E; Pierce, JH; Aaronson, SA; Di Fiore, PP.

It is therefore possible that acquired resistance to anti-estrogens is facilitated by increases of HER1 and HER2 expression enabling stimulation of proliferation via this hormone independent pathway. In the adjuvant setting, several retrospective studies suggest that patients overexpressing HER2 may derive less benefit from adjuvant tamoxifen [66-68]. However this is not a universal finding and studies in both the adjuvant and metastatic settings have limitations, such as the small numbers of patients and the use of inconsistent methods to assess HER2 status [69, 70].

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Aggressive Breast Cancer by Regina H. DeFrina


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